DS Slingo Quest (Cartridge Only)
DS Smart Boy’s Gameroom (Cartridge Only)
DS Smart Boy’s Gameroom CIB
DS Sonic Rush CIB
DS Space Chimps CIB
DS Spectrobes (Cartridge Only)
DS Spectrobes: Beyond the Portals (Cartridge Only)
DS Speed Racer: The Video Game (Cartridge Only)
DS Spider-Man: Friend or Foe CIB
DS SpongeBob SquarePants featuring Nicktoons: Globs of Doom (Cartridge Only)
DS SpongeBob's Atlantis SquarePantis (Cartridge Only)
DS SpongeBob's Atlantis SquarePantis CIB
DS SpongeBob's Boating Bash (Cartridge Only)
DS Spore Creatures (Cartridge Only)
DS Squeeballs Party (Cartridge Only)
DS Squinkies (Cartridge Only)
DS Squishy Tank (Cartridge Only)
DS Star Wars: The Clone Wars - Jedi Alliance (Cartridge Only)
DS Star Wars: The Clone Wars - Republic Heroes (Cartridge Only)
DS Style Lab: Fashion Design CIB
DS Style Lab: Jewelry Design CIB
DS Super Fruit Fall (Cartridge Only)
DS Super Scribblenauts (Cartridge Only)
DS Tak: Mojo Mistake (Cartridge Only)
